|Derma-Med - (Betamethasone/Clotrimazole/Gentamicin)|
Product: Derma-Med Cream
Indications for use: This association is indicated for the relief of inflammatory manifestations of dermatosis responsive to corticotherapy, complicated by secondary infections caused by organisms sensitive to the components of this dermatological preparation or when the possibility of such infection is suspected.
Dosage: Topical on the skin area(s) affected and surrounding areas, twice daily, morning and night. The duration of treatment varies and depends on the extent of disease.
Warnings: Long-term topical use of antibiotics may result in overgrowth of nonsusceptible microorganisms. If this happens or if irritation, hypersensitivity or superinfection occurs with the use of this preparation, the treatment should be discontinued and initiate appropriate therapy.
It has been shown that there is cross-sensitivity between aminoglycosides, so appropriate precautions should be taken.
Any of the side effects associated with systemic use of corticosteroids, including adrenal suppression, may also occur with topical corticosteroids, especially in children and breast-fed. Systemic absorption of topical corticosteroids and gentamicin increase, if applied to large body surface areas or when using occlusive dressing. Avoid application of gentamicin on open wounds or damaged skin.
Pregnancy: Not recommended for use during pregnancy due to possible teratogenicity, especially when used on large body surfaces, in large amounts or for prolonged periods.
Lactancy: May produce systemic effects, such as growth inhibition.
Contraindications: Use of this formula must be avoided in patients with hypersensitivity to any of the ingredients of the formula.
Side/adverse Effects: In very rare cases adverse reactions to treatment have been reported, such as hypochromia, burning, erythema, exudation and pruritus. The following local adverse reactions have also been described with local corticosteroid use, especially when used under occlusive dressings: burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation.
Adverse reactions attributed to clotrimazole include: rash, itching, blistering, peeling, edema, itching and general irritation of the skin.